Hemagglutinin activation of pathogenic avian influenza viruses of serotype H7 requires the protease recognition motif R-X-K/R-R
نویسندگان
چکیده
منابع مشابه
Can high-pathogenic avian influenza viruses with novel hemagglutinin serotypes other than H5 or H7 emerge?
The family Herpesviridae is a large, diverse family of double-stranded enveloped DNA viruses. Herpes B virus (BV) and Cercopithecine herpesvirus 2 (CeHV-2) are simian herpesvi-ruses. Like herpes simplex virus 1 (HSV-1), they belong to the a-herpesvirus subfamily. interest in BV infections results from the observation that zoonotic infections often result in death of humans, whereas infection of...
متن کاملComposition of the Hemagglutinin Polybasic Proteolytic Cleavage Motif Mediates Variable Virulence of H7N7 Avian Influenza Viruses
Acquisition of a polybasic cleavage site (pCS) in the hemagglutinin (HA) is a prerequisite for the shift of low pathogenic (LP) avian influenza virus (AIV) to the highly pathogenic (HP) form in chickens. Whereas presence of a pCS is required for high pathogenicity, less is known about the effect of composition of pCS on virulence of AIV particularly H7N7. Here, we investigated the virulence of ...
متن کاملthe effect of consciousness raising (c-r) on the reduction of translational errors: a case study
در دوره های آموزش ترجمه استادان بیشتر سعی دارند دانشجویان را با انواع متون آشنا سازند، درحالی که کمتر به خطاهای مکرر آنان در متن ترجمه شده می پردازند. اهمیت تحقیق حاضر مبنی بر ارتکاب مکرر خطاهای ترجمانی حتی بعد از گذراندن دوره های تخصصی ترجمه از سوی دانشجویان است. هدف از آن تاکید بر خطاهای رایج میان دانشجویان مترجمی و کاهش این خطاها با افزایش آگاهی و هوشیاری دانشجویان از بروز آنها است.از آنجا ک...
15 صفحه اولSusceptibility of swine to H5 and H7 low pathogenic avian influenza viruses
BACKGROUND The ability of pigs to become infected with low pathogenic avian influenza (LPAI) viruses and then generate mammalian adaptable influenza A viruses is difficult to determine. Yet, it is an important link to understanding any relationship between LPAI virus ecology and possible epidemics among swine and/or humans. OBJECTIVES Assess susceptibility of pigs to LPAI viruses found within...
متن کاملRisk Assessment of the Introduction and Spread of Highly Pathogenic Avian Influenza Viruses (H5-Subtypes) Via Migratory Birds in Iran
Background and Objectives: HPAI has economic and public health importance. Aquatic and shore migratory birds are the main reservoirs and the cause of the spread of viruses across countries. The aim of study was risk assessment of the spread of the avian influenza H5 viruses. Methods: In this qualitative study, structured interviews and focus group discussions were used to assess the risk of...
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ژورنال
عنوان ژورنال: Virology
سال: 1992
ISSN: 0042-6822
DOI: 10.1016/0042-6822(92)90775-k